Francois Jacob

Francois Jacob (1920- )

Background Info---

- Borned in Nancy, France on June 17, 1920.

-Abandoned Medical School due to the out break of WWII and moved to work in London.

-He then enlisted in Franch army as an army doctor and wounded in Normandy battle.

-He was honored with the highest Croix de la Libération.

-Due to his wounded hand he was precluded being a surgon, thus, he became a research biologist.

Year Became Famous---

In 1965, he was granted with The Nobel Prize in Physiology or Medicine along with two other scientists.

Publication Made Him Famous---

- E. coli bacterium represses production of enzymes involved in lactose metabolism when lactose is not available.

-controling of enzyme levels in all cells happens through feedback on transcription.

Contribution to World Genetics---

 Jacob and Monod made key experimental and theoretical discoveries that demonstrated that in the case of the lactose system outlined above (in the bacterium E. coli), there are specific proteins that are devoted to repressing the transcription of the DNA to its product (RNA, which in turn is decoded into protein).

Works Cited

2010. Francois Jacob.  September 18, 2010  http://www.nndb.com/people/157/000129767/

François Jacob-Bioraphy. Nobelprize.org. September 18, 2010 http://nobelprize.org/nobel_prizes/medicine/laureates/1965/jacob-bio.html